Recently, Professor Pang Daiwen and his team proposed a multi-level control strategy for the photoluminescence quantum yield (PLQY) of quantum dot-polymer composite nanospheres, including adjusting quantum dot ligands, precisely controlling free radical concentrations, and constructing a polymer crosslinking structure to improve compatibility and reduce surface defects. They successfully achieved a world record level of 97.6% PLQY, breaking through the current bottleneck of 65%. This achievement paves the way for large-scale production of high-brightness quantum dot-polymer composites and expands their application potential in biomedical detection. The related results are published in the Journal of the American Chemical Society (JACS) under the title “Achieving Near 100% Photoluminescence Quantum Yield in Quantum Dot Nanospheres through Multi-Level Regulation” and are selected as the cover article.