Rapid Detection: Aiding Epidemic Prevention and Control

Professor Pang Daiwen and Professor Liu Dingbin from the College of Chemistry at Nankai University have developed test strip technologies based on quantum dots and colloidal gold growth for the visual rapid detection of novel coronavirus antigens (N protein, S protein) and antibodies (IgM, IgG). Currently, the construction of magnetic quantum dot probes (three-layer quantum dots) has been completed, and the detection limit for antigens on the test strip can reach 100 ng/mL; a test strip detection technology for colloidal gold in situ growth has been developed. The detection sensitivity is 100 times higher than that of conventional colloidal gold methods; the detection limit for N protein can reach 100 ng/mL; the detection sensitivity for S protein can reach 10 ng/mL; the two detection methods for antigens and antibodies are currently undergoing clinical sample testing at the Hubei Provincial Center for Disease Control and Prevention.