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Prof. Dr. Jiantong Dong

Date of birth: 1992.10

Work Address:

Research Interest: Pathogen & Exosome Detection, Microfluidic Chips, Dynamic Nucleic Acids, Biosensing, and Imaging

E-mail: jtdong@pku.edu.cn

Education


Shandong University, Chemistry, B. S.
Peking University, Analytical Chemistry, Ph.D.
University of California, Los Angeles, Visiting student.


Academic Career

Hebrew University of Jerusalem, Institute of Chemistry, Postdoctoral Researcher

Nankai University, College of Chemistry, Researcher, Doctoral Supervisor

 


Honors and Awards
Publications

1. J. Dong, I. Willner*, Photochemically Triggered, Transient, and Oscillatory Transcription Machineries Guide Temporal Modulation of Fibrinogenesis, J. Am. Chem. Soc., 2025, 147, 2216–2227.

2. J. Dong, I. Willner*, Transient Transcription Machineries Modulate Dynamic Functions of G-Quadruplexes: Temporal Regulation of Biocatalytic Circuits, Gene Replication and Transcription, Angew. Chem. Int. Ed., 2023, 62(33): e202307898

3. M. Ji, J. Dong*, Z. Ye, J. Kang, G. Han, X. Hong, Y, Wei, X, Chen*, W. Sun*, D. Liu*, Endogenous HClO-Gated Cascade MicroRNA Imaging for Precise Diagnosis of Atherosclerosis In Vivo, J. Am. Chem. Soc., 2025, DOI: 10.1021/jacs.5c00031

4. H. Liu#, J. Dong#, Z. Duan, F. Xia*, I. Willner*, F. Huang*, Light-Activated CRISPR-Cas12a for Amplified Imaging of MicroRNA in Cell Cycle Phases at Single-Cell Levels, Sci. Adv., 2024, 10, eadp6166.

5. J. Dong, I. Willner*, Dynamic Transcription Machineries Guide the Synthesis of Temporally Operating DNAzymes, Gated and Cascaded DNAzyme Catalysis, ACS Nano, 2023, 17, 687696.

6. J. Dong, Y. Ouyang, J. Wang, M. P. OHagan, I. Willner*, Assembly of Dynamic Gated and Cascaded Transient DNAzyme Networks, ACS Nano, 2022, 16, 61536164.

7. J. Dong, M. P. OHagan, I. Willner*, Switchable and Dynamic G-Quadruplexes and Their Applications, Chem. Soc. Rev., 2022, 51, 76317661.

8. J. Dong, J.-F. Chen, M. Smalley, M. Zhao, Z. Ke*, Y. Zhu*, H.-R. Tseng*, Nanostructured Substrates for Detection and Characterization of Circulating Rare Cells: From Materials Research to Clinical Applications, Adv. Mater., 2020, 32, 1903663.

9. J. Dong, R. Y. Zhang, N. Sun, J. Hu, M. D. Smalley, A. Zhou, Y. Hua, W. Rothermich, M. Chen, J. Chen, J. Ye, P.-C. Teng, D. Qi, J. A. Toretsky, J. S. Tomlinson, M. Li, P. S. Weiss, S. J. Jonas, N. Federman, L. Wu, M. Zhao*, H-.R. Tseng*, Y. Zhu*, Coupling Nanostructured Microchips with Covalent Chemistry Enables Purification of Sarcoma-Derived Extracellular Vesicles for Downstream Functional Studies, Adv. Funct. Mater., 2020, 30, 2003237.

10. J. Dong, Y. J. Jan, J. Cheng, R. Y. Zhang, M. Meng, M. Smalley, P.-J. Chen, X. Tang, P. Tseng, L. Bao, T.-Y. Huang, D. Zhou, Y. Liu, X. Chai, H. Zhang, A. Zhou, V. G. Agopian, E. M. Posadas, J.-J. Shyue, S. J. Jonas, P. S. Weiss, M. Li*, G. Zheng*, H.-h. Yu*, M. Zhao*, H.-R. Tseng*, Y. Zhu*, Covalent Chemistry on Nanostructured Substrates Enables Noninvasive Quantification of Gene Rearrangements in Circulating Tumor Cells, Sci. Adv., 2019, 5, eaav9186.

11. Y. Afshar#, J. Dong#, P. Zhao, L. Li, S. Wang, R. Y. Zhang, C. Zhang, O. Yin, C. S. Han, B. D. Einerson, T. L. Gonzalez, H. Zhang, A. Zhou, Z. Yang, S.-J. Chou, N. Sun, J. Cheng, H. Zhu, J. Wang, T. X. Zhang, Y.-T. Lee, J. J. Wang, P.-C. Teng, P. Yang, D. Qi, M. Zhao, M.-S. Sim, R. Zhe, J. D. Goldstein, J. Williams, X. Wang, Q. Zhang, L. D. Platt, C. Zou*, M. D. Pisarska*, H.-R. Tseng*, Y. Zhu*, Circulating Trophoblast Cell Clusters for Early Detection of Placenta Accreta Spectrum Disorders, Nat. Commun., 2021, 12, 4408.


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