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Prof. Dr. Jiantong Dong

Date of birth: 1992.10

Work Address:

Research Interest: Pathogens & Exosomes, Microfluidic Chip, Dynamic Nucleic Acid Assembly, Biosensing and Imaging, Precision Medicine Analysis.

E-mail: jtdong@pku.edu.cn

Education


2010-2014 Shandong University, Chemistry, B. S.
2014-2021 Peking University, Analytical Chemistry, Ph.D.
2017-2019 University of California, Los Angeles, Visiting Graduate Student.


Academic Career

2021-2025 Hebrew University of Jerusalem, Institute of Chemistry, Postdoctoral Researcher

Since 2025 Nankai University, College of Chemistry, Researcher, Doctoral Supervisor

 


Honors and Awards
Representative Publications

1. J. Dong, I. Willner*, Dynamic Transcription Frameworks, Nat. Chem., 2025, in press.

2. J. Dong, F. Xia*, F. Huang*, and I. Willner*, Dynamic Transcription Machineries in Protocells, J. Am. Chem. Soc., 2025, DOI: 10.1021/jacs.5c03622.

3. J. Dong, I. Willner*, Photochemically Triggered, Transient, and Oscillatory Transcription Machineries Guide Temporal Modulation of Fibrinogenesis, J. Am. Chem. Soc., 2025, 147, 2216–2227.

4. J. Dong, I. Willner*, Transient Transcription Machineries Modulate Dynamic Functions of G-Quadruplexes: Temporal Regulation of Biocatalytic Circuits, Gene Replication and Transcription, Angew. Chem. Int. Ed., 2023, 62, e202307898.

5. J. Dong, Y. J. Jan, J. Cheng, R. Y. Zhang, M. Meng, M. Smalley, P.-J. Chen, X. Tang, P. Tseng, L. Bao, T.-Y. Huang, D. Zhou, Y. Liu, X. Chai, H. Zhang, A. Zhou, V. G. Agopian, E. M. Posadas, J.-J. Shyue, S. J. Jonas, P. S. Weiss, M. Li*, G. Zheng*, H.-h. Yu*, M. Zhao*, H.-R. Tseng*, and Y. Zhu*, Covalent Chemistry on Nanostructured Substrates Enables Noninvasive Quantification of Gene Rearrangements in Circulating Tumor Cells, Sci. Adv., 2019, 5, eaav9186.

6. J. Dong#, J.-F. Chen#, M. Smalley, M. Zhao, Z. Ke*, Y. Zhu*, and H.-R. Tseng*, Nanostructured Substrates for Detection and Characterization of Circulating Rare Cells: From Materials Research to Clinical Applications, Adv. Mater., 2020, 32, 1903663.

7. J. Dong, M. P. OHagan, and I. Willner*, Switchable and Dynamic G-Quadruplexes and Their Applications, Chem. Soc. Rev., 2022, 51, 76317661.

8. J. Dong, I. Willner*, Dynamic Transcription Machineries Guide the Synthesis of Temporally Operating DNAzymes, Gated and Cascaded DNAzyme Catalysis, ACS Nano, 2023, 17, 687696.

9. J. Dong, Y. Ouyang, J. Wang, M. P. OHagan, and I. Willner*, Assembly of Dynamic Gated and Cascaded Transient DNAzyme Networks, ACS Nano, 2022, 16, 61536164.

10. J. Dong, R. Y. Zhang, N. Sun, J. Hu, M. D. Smalley, A. Zhou, Y. Hua, W. Rothermich, M. Chen, J. Chen, J. Ye, P.-C. Teng, D. Qi, J. A. Toretsky, J. S. Tomlinson, M. Li, P. S. Weiss, S. J. Jonas, N. Federman, L. Wu, M. Zhao*, H-.R. Tseng*, Y. Zhu*, Coupling Nanostructured Microchips with Covalent Chemistry Enables Purification of Sarcoma-Derived Extracellular Vesicles for Downstream Functional Studies, Adv. Funct. Mater., 2020, 30, 2003237.

11. M. Ji, J. Dong*, Z. Ye, J. Kang, G. Han, X. Hong, Y, Wei, X, Chen*, W. Sun*, and D. Liu*, Endogenous HClO-Gated Cascade MicroRNA Imaging for Precise Diagnosis of Atherosclerosis In Vivo, J. Am. Chem. Soc., 2025, 147, 7113–7126. (*co-corresponding author)

12. X. Wang, J. Dong*, J. Kang, X. Chen, X. Hong, J. Chen, W. Du, H. Cai, and D. Liu*, Self-Adaptive Release of Stem Cell-Derived Exosomes from a Multifunctional Hydrogel for Accelerating MRSA-Infected Diabetic Wound Repair, J. Am. Chem. Soc., 2025, 147, 16362–16378. (*co-corresponding author)

13. H. Liu#, J. Dong#, R. Wu#, J. Dai*, X. Lou, F. Xia, I. Willner*, and F. Huang*, Light-Triggered CRISPR/Cas12a for Genomic Editing and Tumor Regression, Angew. Chem. Int. Ed., 2025, e202502892. (#co-first author)

14. H. Liu#, J. Dong#, Z. Duan, F. Xia*, I. Willner*, and F. Huang*, Light-Activated CRISPR-Cas12a for Amplified Imaging of MicroRNA in Cell Cycle Phases at Single-Cell Levels, Sci. Adv., 2024, 10, eadp6166. (#co-first author)

15. Y. Afshar#, J. Dong#, P. Zhao, L. Li, S. Wang, R. Y. Zhang, C. Zhang, O. Yin, C. S. Han, B. D. Einerson, T. L. Gonzalez, H. Zhang, A. Zhou, Z. Yang, S.-J. Chou, N. Sun, J. Cheng, H. Zhu, J. Wang, T. X. Zhang, Y.-T. Lee, J. J. Wang, P.-C. Teng, P. Yang, D. Qi, M. Zhao, M.-S. Sim, R. Zhe, J. D. Goldstein, J. Williams, X. Wang, Q. Zhang, L. D. Platt, C. Zou*, M. D. Pisarska*, H.-R. Tseng*, and Y. Zhu*, Circulating Trophoblast Cell Clusters for Early Detection of Placenta Accreta Spectrum Disorders, Nat. Commun., 2021, 12, 4408. (#co-first author)



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